A genome-based strategy uncovers frequent BRAF mutations in melanoma

Autoria(s): Pollock, Pamela M.; Meltzer, Paul S.
Data(s)

2002
Resumo

Using a genome-scanning approach to search for oncogenes, a recent report identifies somatic mutations in the signaling gene BRAF that are particularly prevalent in melanoma.
Identificador

http://eprints.qut.edu.au/45820/
Publicador

Cell Press
Relação

DOI:10.1016/S1535-6108(02)00089-2

Pollock, Pamela M. & Meltzer, Paul S. (2002) A genome-based strategy uncovers frequent BRAF mutations in melanoma. Cancer Cell, 2(1), pp. 5-7.
Fonte

Cell & Molecular Biosciences; Faculty of Science and Technology; Institute of Health and Biomedical Innovation
Palavras-Chave #111201 Cancer Cell Biology #Cell Transformation #Neoplastic #Humans #Melanoma/enzymology/ genetics/metabolism/pathology #Mitogen-Activated Protein Kinases/metabolism #Models #Biological #Mutation #Point Mutation/genetics #Protein Structure #Tertiary #Proto-Oncogene Proteins B-raf #Proto-Oncogene Proteins c-raf/chemistry/ genetics/metabolism #Signal Transduction #Tumor Cells #Cultured #ras Proteins/metabolism
Tipo

Journal Article
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